The inhibition of factor inhibiting hypoxia-inducible factor (FIH) by beta-oxocarboxylic acids.

Symplectic ID: 
33292
Source: 
PubMed
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1
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Saturday, 5 September, 2026 - 18:44
DOI: 
10.1039/b510707e
Publication Date: 
Monday, 21 November, 2005
First Page: 
5438
Last Page: 
5440
Keywords: 
Carboxylic Acids
Models, Molecular
Oxygenases
Protein Biosynthesis
Protein Structure, Tertiary
Repressor Proteins
Transcription Factors
Authors: 
Banerji, B
Conejo-Garcia, A
McNeill, LA
McDonough, MA
Buck, MRG
Hewitson, KS
Oldham, NJ
Schofield, CJ
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0
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Abstract: 
Cyclic beta-oxocarboxylic acids inhibit factor inhibiting hypoxia-inducible factor via ligation to the active site iron.
ISSN: 
1359-7345
Journal Title: 
Chem Commun (Camb)
Issue: 
43
ID at Source: 
16261239
Publication Status: 
Published
Open access: 
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