The synthesis of polyhydroxylated amino acids from glucuronolactone: enantiospecific syntheses of 2s, 3r, 4r, 5s-trihydroxypipecolic acid, 2r, 3r, 4r, 5s-trihydroxypipecolic acid and 2r, 3r, 4r-dihydroxyproline

Bashyal BP, Chow HF, Fellows LE, Fleet GWJ

The potential of D-glucuronolactone for the synthesis of polyhydroxylated amino acids is illustrated by the enantiospecific syntheses of 2S,3R,4R,5S-trihydroxy-pipecolic acid, 2R, 3R, 4R, 5S-trihydroxypipecolic acid and 2R,3R,4R-dihydroxyproline. © 1987.